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For Providers

Your Partner in Preventing Diabetic Limb Loss

Supporting Foot Health Through Proactive Monitoring

At Orpyx®, we are committed to improving foot health for individuals living with diabetes. We are focused on helping to prevent diabetic foot complications, including limb loss, through early detection, continuous monitoring, and proactive care.

The Orpyx Sensory Insole program combines advanced sensory insoles with remote patient monitoring to support proactive care. The system continuously monitors plantar pressure, temperature, and activity data, while our US-based nursing team reviews trends and supports patient adherence.

For patients, the system is simple and doesn't require charging. For the provider, we deliver trusted support that keeps you and your patient connected between medical visits.

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A Shared Vision for Ending Limb Loss

How the Technology Works

The Only Plantar RPM Solution Backed by a Randomized Controlled Trial¹

In a randomized controlled trial (RCT) of patients with diabetes and a history of foot ulcers, the Orpyx technology, delivering real-time pressure alerts, demonstrated a substantial reduction in ulcer recurrence.

Among patients who wore the insoles for at least 4.5 hours per day, ulcer incidence was reduced by 86% compared to standard care.¹

This highlights the critical role of consistent use and real-time data in supporting early intervention and long-term limb preservation.

View RCT

The Patient Experience

Empowering People. Supporting Providers.

Our Between Visit Services provides trusted support that keeps you and your patient connected between visits, because your care doesn’t stop when the appointment ends.

Ongoing Personalized Coaching
Orpyx US-based nurses support the users foot care plan and help them make healthy changes that fit their lifestyle.

Flexible Communication Options
Every user is assigned a remote nurse for personalized support via phone or text.

Proactive Behavior Modification
Our remote nurses spot concerns early and guide changes to help prevent foot complications and avoid more serious interventions.

Scheduled and As-Needed Calls
Our remote nurses conduct monthly wellness calls to monitor and identify early foot health concerns before escalation.

Minimal Escalation
Only 4% of cases are escalated to the provider, as nurses support patients through early intervention and education.2

Actionable Insights
Multimodal insole data offers actionable insights to help inform the users foot care plan.

Clinical Rounds
We host collaborative clinical rounds to interpret RPM data, leveraging informatics to uncover insights, guide decisions, and enhance outcomes and engagement.

Seamless, Secure Integration
Our program integrates seamlessly into your workflows, providing secure, encrypted, HIPAA-compliant data.

Real Experiences. Real Impact.

Dr. Jonathan Rouse, DPM
Foot & Ankle Center of Nebraska & Iowa
Dr. David G. Armstrong DPM, MD, PhD
Keck School of Medicine of USC
Dr. Jeffrey Gewirtz, DPM
Medical Director, Curalta Foot & Ankle

Being in the program helped me figure out I was wearing the wrong shoes. It has really changed the way I'm walking. I don't get as tired now. My shoes feel really comfortable, I really enjoy these insoles.

Orpyx Sensory Insole Customer

A lot of people that I show the phone to say, "how are you doing that?" I tell them there are sensors in my shoe that register on my phone, and a lot of people say, "how do I get into this program?

Orpyx Sensory Insole Customer

It keeps your feet top of mind. Check them. Don't just put it off until something goes bad, where you should have had a chance to get it treated before it gets worse.

Orpyx Sensory Insole Customer
Catherine Casas
Medical Assistant Training Manager, Curalta Foot & Ankle

Managing diabetes is really complicated and as a patient you’re responsible for doing so many things that feel like they’re not making a difference. The reports screen on the digital display is great because I can use it to set manageable and achievable personal goals and track my progress. It feels good to be able to see/know I’ve met the goal and am actually accomplishing something and making a positive contribution to better outcomes.

Orpyx Sensory Insole Customer

I love the fact that I am being checked on. The staff is gracious and kind, as well as understanding of my needs and day to days. I feel confident knowing they're checking on me, and watching for things I might not know and it is being documented, I truly appreciate it.

Orpyx Sensory Insole Customer

To be able to be alerted about a temperature or pressure increase with our patients has been a great benefit. It has allowed us to get them seen in the office sooner than their appointment and educate them about their foot health.

Catherine Casas
Medical Assistant Training Manager, Curalta Foot & Ankle

I like the fact that things are being monitored and it is preventative.

Orpyx Sensory Insole Customer

I love them, they're very comfortable and it's been a great experience.

Orpyx Sensory Insole Customer

These (insoles) are more comfortable than other orthotics I've worn before.

Orpyx Sensory Insole Customer

[Orpys Sensory Insoles] are very simple… Comfortable to wear, you just forget that they're there – part of your shoe and your everyday life, and it's just great to be able to have the feedback on the phone and see how those impact my walking.

Patient Pat

Everyone at Orpyx is very friendly, very kind, and very knowledgeable. I've had good experiences with the help offered by my Orpyx Nurse and from the Customer Care Team.

Orpyx Sensory Insole Customer

The patients enjoy talking to the remote monitoring team, they all say the insoles are very comfortable, and more than 90% of them are wearing them every day. I speak to them from a customer service standpoint on behalf of the practice, and all of the feedback I get is how helpful Orpyx has been, how quick they are to respond to any issues and answer any questions they have.

Catherine Casas
Medical Assistant Training Manager, Curalta Foot & Ankle

My walking has improved and the calluses that were already on my feet are not hurting nearly as much as they did. I am feeling better and much more comfortable. I can tell the actual skin is growing better than it was.

Orpyx Sensory Insole Customer

I like that I can watch on my phone as I'm walking, see the pressure points on my feet, and the alerts that come up when I'm putting too much pressure on my foot, or both feet because of whatever activity I'm doing. You can change your habit right there. It's a great tool to use to try to correct any bad habits you have for walking.

Patient Pat

The device is convenient… I can take them out of my tennis shoes and put them right in my work boots, and they can monitor what I’m doing during the day and how many steps I’m taking.

Patient Joe

We have to adopt better technologies and [Orpyx Sensory Insoles] are definitely one of those technologies. Our patients will benefit from these major jumps in digital health. The potential is game changing for the diabetic population.

Dr. Brock Liden
DPM, ABPM, FAPWCA

The onboarding went really well, I was skeptical of the product at first, but it is doing a good job. The insoles are comfortable and don’t have any pinching points or anything like that.

Patient Joe

The remote patient monitoring that these inserts now allow us to use will save limbs and lives. They are a great asset to the practice of podiatric medicine and medicine in general, and a great asset for our patients because their quality of life will be greatly improved.

Dr. Matthew G. Garoufalis
DPM, FASPS, FACPM, CWS, FFPM RCPS (Glasg)

I discovered I was a diabetic at 35… and I could not believe what I found out about diabetes in your feet. You can’t believe how detrimental pressure is to your feet. [With Orpyx Sensory Insoles] you can keep track of what's going on with your feet all the time and believe you and me, you need it all the time.

Patient Larry

CPT® Code Considerations*

CPT® 99453

Initial set up and patient education on use of medical device

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Billing Frequency
One time only; requires 16 days of data in 30 day period
CPT® 99454

Supply of medical device with daily recordings and programmed alerts

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Billing Frequency
One time per 30 day period
CPT® 99457

RPM services; first 20 minutes

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Billing Frequency
First 20 minutes of RPM services, including one interactive communication, per calendar month
CPT® 99458

RPM services; additional 20 minutes

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Billing Frequency
For each additional 20 minutes of RPM services, per calendar month

Learn More About the Orpyx Sensory Insole Program

1. Abbot CA, et al. Innovative intelligent insole system reduces diabetic foot ulcer recurrence at plantar sites: a prospective, randomised, proof-of-concept study. Lancet Digital Health Oct. 2019; 1: e308–18. (Study was conducted with first generation SurroSense Rx® which has the same pressure algorithm as the Orpyx technology) 2. Data on file—Escalations Analysis 2024. *The reimbursement information provided is intended to provide general information concerning coding of Orpyx products only. Orpyx does not guarantee coverage or payment for any products. The ultimate responsibility for proper coding, satisfying reimbursement requirements, and obtaining reimbursement remains with the provider. Coding and coverage policies and guidelines are complex, can vary from one carrier or region to another, and are updated frequently. Providers should check with their local carriers or intermediaries often and should consult with counsel, a reimbursement specialist for coding, coverage, or billing questions. Current Procedural Terminology (CPT®) is copyright by the American Medical Association. All rights reserved. CPT is a registered trademark of the American Medical Association (AMA). CPT codes and their descriptions do not reflect or guarantee coverage or payment.